:root{
  --pharma-bg:#f6f8fb; --pharma-card:#fff; --pharma-ink:#1f2a37; --pharma-muted:#5b6776;
  --pharma-line:#e3e8ef; --pharma-primary:#0f6f6e; --pharma-primary-2:#0a5554;
  --pharma-accent:#c2410c; --pharma-soft:#eaf4f3; --pharma-warn:#fff8e6; --pharma-warn-bd:#f0d27a;
}
*{box-sizing:border-box}
html,body{margin:0;padding:0}
body{
  background:var(--pharma-bg); color:var(--pharma-ink);
  font-family:-apple-system,BlinkMacSystemFont,"Segoe UI",Roboto,Helvetica,Arial,sans-serif;
  font-size:16px; line-height:1.6;
}
a{color:var(--pharma-primary); text-decoration:none}
a:hover{text-decoration:underline}
h1,h2,h3{line-height:1.25; color:var(--pharma-ink); margin:1.4em 0 .5em}
h1{font-size:clamp(1.6rem,4vw,2.4rem)}
h2{font-size:clamp(1.3rem,3vw,1.8rem)}
h3{font-size:1.15rem}
p{margin:.5em 0}
ul{margin:.5em 0; padding-left:1.25em}
img{max-width:100%; height:auto}

/* ── header ── */
.pharma-header{
  position:sticky; top:0; z-index:50;
  background:var(--pharma-primary); color:#fff;
  box-shadow:0 1px 0 rgba(0,0,0,.08);
}
.pharma-header__inner{
  max-width:1180px; margin:0 auto; padding:.55rem 1rem;
  display:flex; align-items:center; gap:1rem; min-width:0;
}
.pharma-brand{
  color:#fff; font-weight:700; font-size:1.15rem; letter-spacing:.01em;
  white-space:nowrap;
}
.pharma-nav{display:flex; gap:.15rem; flex-wrap:wrap; min-width:0}
.pharma-nav a{
  color:#fff; opacity:.92; padding:.35rem .6rem; border-radius:6px; font-size:.95rem;
}
.pharma-nav a:hover{background:rgba(255,255,255,.14); text-decoration:none}
.pharma-header__cta{
  margin-left:auto; display:inline-flex; align-items:center; gap:.4rem;
  background:var(--pharma-accent); color:#fff; font-weight:600;
  padding:.5rem .9rem; border-radius:8px; white-space:nowrap;
}
.pharma-header__cta:hover{background:#9a3412; text-decoration:none}
.pharma-header__cta svg{width:16px;height:16px;flex:0 0 auto}

/* ── hero ── */
.pharma-hero{
  background:linear-gradient(180deg, var(--pharma-soft), var(--pharma-bg));
  border-bottom:1px solid var(--pharma-line);
}
.pharma-hero__inner{
  max-width:1180px; margin:0 auto; padding:1.6rem 1rem 1.2rem; min-width:0;
  display:grid; grid-template-columns:minmax(0,1fr) auto; gap:1.2rem; align-items:center;
}
.pharma-hero h1{margin:0}
.pharma-hero p{color:var(--pharma-muted); margin:.4rem 0 0; max-width:60ch}
.pharma-hero__cta{
  display:inline-flex; align-items:center; gap:.45rem;
  background:var(--pharma-accent); color:#fff; font-weight:700;
  padding:.75rem 1.2rem; border-radius:10px; font-size:1.02rem; white-space:nowrap;
  box-shadow:0 2px 6px rgba(194,65,12,.25);
}
.pharma-hero__cta:hover{background:#9a3412; text-decoration:none}

/* ── layout ── */
.pharma-wrap{
  max-width:1180px; margin:0 auto; padding:1.2rem 1rem 4rem; min-width:0;
  display:grid; grid-template-columns:minmax(0,1fr) 280px; gap:1.5rem;
}
.pharma-main{min-width:0}
.pharma-content{
  background:var(--pharma-card); border:1px solid var(--pharma-line);
  border-radius:12px; padding:1.2rem 1.4rem; min-width:0;
}
.pharma-content h1:first-child{margin-top:.2em}
.pharma-content table{border-collapse:collapse; width:100%; margin:.6em 0}
.pharma-content th,.pharma-content td{border:1px solid var(--pharma-line); padding:.45rem .6rem; text-align:left; vertical-align:top}
.pharma-content th{background:var(--pharma-soft); font-weight:600}
.pharma-content blockquote{
  margin:1em 0; padding:.7rem 1rem; border-left:4px solid var(--pharma-primary);
  background:var(--pharma-soft); border-radius:0 8px 8px 0; color:var(--pharma-ink);
}

/* gallery */
.pharma-gallery{
  display:grid; grid-template-columns:repeat(auto-fill,minmax(140px,1fr)); gap:.8rem; margin:1rem 0;
}
.pharma-gallery__item{display:block; border:1px solid var(--pharma-line); border-radius:8px; overflow:hidden; background:var(--pharma-bg)}
.pharma-gallery__item img{display:block; width:100%; aspect-ratio:4/3; object-fit:cover}
.pharma-gallery a.pharma-gallery__item:hover{text-decoration:none; border-color:var(--pharma-primary)}

/* ── sidebar ── */
.pharma-aside{min-width:0; display:flex; flex-direction:column; gap:1rem}
.pharma-card{
  background:var(--pharma-card); border:1px solid var(--pharma-line);
  border-radius:10px; padding:.9rem 1rem; min-width:0;
}
.pharma-card h3{margin:.1rem 0 .5rem; font-size:1rem}
.pharma-card ul{margin:0; padding-left:1.1em; list-style:disc}
.pharma-card li{margin:.18rem 0}
.pharma-card .pharma-card__cta{
  display:block; text-align:center; margin-top:.7rem;
  background:var(--pharma-accent); color:#fff; font-weight:600;
  padding:.55rem .8rem; border-radius:8px;
}
.pharma-card .pharma-card__cta:hover{background:#9a3412; text-decoration:none}
.pharma-aside .pharma-warn{
  background:var(--pharma-warn); border:1px solid var(--pharma-warn-bd);
  border-radius:10px; padding:.8rem .9rem; font-size:.9rem; color:#7a5a16;
}

/* ── sticky CTA bar (mobile) ── */
.pharma-cta-bar{
  position:sticky; bottom:0; z-index:40;
  background:var(--pharma-primary); color:#fff;
  display:none; align-items:center; gap:.6rem;
  padding:.6rem .9rem; box-shadow:0 -2px 8px rgba(0,0,0,.12);
}
.pharma-cta-bar__txt{font-size:.92rem; line-height:1.3; min-width:0; flex:1 1 auto}
.pharma-cta-bar__txt strong{display:block; font-size:1rem}
.pharma-cta-bar__btn{
  background:var(--pharma-accent); color:#fff; font-weight:700;
  padding:.6rem 1rem; border-radius:8px; white-space:nowrap; flex:0 0 auto;
}
.pharma-cta-bar__btn:hover{background:#9a3412; text-decoration:none}

/* ── footer ── */
.pharma-footer{
  background:var(--pharma-primary-2); color:#d7e6e5; padding:1.4rem 1rem;
}
.pharma-footer__inner{
  max-width:1180px; margin:0 auto; min-width:0;
  display:flex; flex-wrap:wrap; gap:1rem; justify-content:space-between; align-items:center;
}
.pharma-footer a{color:#eaf4f3}
.pharma-footer__links{display:flex; flex-wrap:wrap; gap:.4rem .9rem; font-size:.92rem}
.pharma-footer__copy{opacity:.8; font-size:.85rem}

@media (max-width:920px){
  .pharma-wrap{grid-template-columns:minmax(0,1fr)}
  .pharma-aside{order:2}
  .pharma-hero__inner{grid-template-columns:minmax(0,1fr)}
  .pharma-hero__cta{justify-self:start}
}
@media (max-width:768px){
  .pharma-header__inner{flex-wrap:wrap; padding:.5rem .7rem}
  .pharma-nav{order:3; width:100%; padding-top:.3rem; border-top:1px solid rgba(255,255,255,.18)}
  .pharma-header__cta{margin-left:0; padding:.45rem .7rem; font-size:.92rem}
  .pharma-content{padding:1rem .9rem}
  .pharma-cta-bar{display:flex}
  .pharma-footer__inner{flex-direction:column; align-items:flex-start}
}


html{ -webkit-text-size-adjust:100%; text-size-adjust:100%; }
body{ overflow-x:hidden; }
img,video,iframe,svg{ max-width:100%; height:auto; }
main,article,section,aside,header,nav,footer{ min-width:0; }
@media (max-width:768px){
  [class*="layout"],[class*="container"],[class*="grid"],[class*="content"],[class*="wrapper"],[class*="main"],[class*="row"]{ min-width:0; }
  pre,table{ min-width:0; max-width:100%; }
  pre{ overflow-x:auto; }
  table{ display:block; overflow-x:auto; }
  code,kbd,samp{ word-break:break-word; }
  [class*="ticker"]{ overflow:hidden; }
  [class*="ticker"] *{ min-width:0; }
}